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Books > Science & Mathematics > Biology, life sciences > Molecular biology
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Laboratory Exercises in Molecular Pathology (Hardcover)
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Laboratory Exercises in Molecular Pathology (Hardcover)
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Laboratory Exercises in Molecular Pathology is organized by major
organ systems and disease type, presenting exercises that distill
essential disease-specific information (related to frequency, risk
factors, disease manifestations) and a description of disease
pathogenesis (molecular and cellular) that is based upon accepted
principles from today's literature. Each exercise is illustrated
with (1) gross specimens, (2) microscopic histopathology, (3)
immunohistochemistry and/or in situ hybridization (when
applicable), (4) laboratory techniques to probe the molecular
nature of the pathological lesions, and (5) molecular diagnostics
(when applicable). In addition, each exercise contains one or more
cases studies to provide students with exposure to the clinical
workup of a patient that are based upon physical examination
findings, traditional pathological analysis, and state-of-the-art
molecular assessment. The laboratory techniques included emphasize
the dissection of molecular and cellular pathogenesis of the
disease in question. Hence, students will see examples of
laboratory results that illustrate how pathways were elucidated.
Further, the sections on molecular diagnostics illustrate how
molecular testing exploits what is known about molecular
pathogenesis in a specific disease setting.
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