Handbook of Clinical Neurology: Spinal Cord Injury summarizes
advances in the clinical diagnosis, monitoring, prognostication,
treatment, and management of spinal cord injuries. More
specifically, it looks at new and important developments in areas
such as high-resolution noninvasive neuroimaging, surgery, and
electrical stimulation of motor, respiratory, bladder, bowel, and
sexual functions. It also reviews the latest insights into
spontaneous regeneration and recovery of function following
rehabilitation, with emphasis on novel therapeutic strategies, such
as gene therapy, transcranial stimulation, brain-machine
interfaces, pharmacological approaches, molecular target discovery,
and the use of olfactory ensheathing cells, stem cells, and
precursor cells. Organized in five sections, the book begins with
an overview of the development, maturation, biomechanics, and
anatomy of the spinal cord before proceeding with a discussion of
clinical diagnosis and prognosis as well as natural recovery,
ambulation, and function following spinal cord injury. It then
examines clinical neurophysiology in the prognosis and monitoring
of traumatic spinal cord injury; medical, surgical and
rehabilitative management of spinal cord trauma; and some new
approaches for improving recovery in patients, including
restoration of function by electrical stimulation, locomotor
training, and the use of robotics. Other chapters cover cell
transplantation, artificial scaffolds, experimental pharmacological
interventions, and molecular and combinatorial strategies for
repairing the injured spinal cord. This volume should be of
interest to neuroscience and clinical neurology research
specialists and practicing neurologists.
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