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Fortschritte Der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progres Dans La Chimie DES Substances Organiques Naturelles (English, German, Paperback, Softcover reprint of the original 1st ed. 1966)
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Fortschritte Der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progres Dans La Chimie DES Substances Organiques Naturelles (English, German, Paperback, Softcover reprint of the original 1st ed. 1966)
Series: Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, 24
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During the past three decades the organic chemist has become in-
creasingly used to take advantage of more and more complex
instrumenta- tion and physical measurements in lieu of laborious,
time-consuming and often ambiguous chemical transformations. Mass
spectrometry is perhaps the most recent, most complex and most
expensive addition to this field. In view of the astonishingly
quick acceptance of nuclear magnetic reso- nance by the organic
chemist it is, in retrospect, surprising that he has neglected mass
spectrometry for such a long time. This can be explained, in part,
by the complexity of the instrumentation and some technical
shortcomings of the earlier commercially available instruments but,
to an even greater extent, it reflects also the prejudices against
a technique that was originally mainly used for quantitative gas
analysis. The usefulness of mass spectrometry as a qualitative
technique in organic chemistry rather than a tool for quantitative
analysis was more and more recognized towards the end of the last
decade. A rather spectacular development followed during the
intervening few years to the point that now any reasonably well
equipped modern organic laboratory is supplied with, or at least
has access to, one or more mass spectrometers suitable for work on
organic compounds. Within the realm of organic chemistry the
technique has become much more important, if not indispensable, for
the natural products chemist while its application to synthetic
problems is much less pro- nounced.
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