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Safety and Efficacy of Non-Prescription (OTC) Analgesics and NSAIDs - Proceedings of the International Conference held at The South San Francisco Conference Center, San Francisco, CA, USA on Monday 17th March 1997 (Paperback, Softcover reprint of the original 1st ed. 1998)
Loot Price: R4,401
Discovery Miles 44 010
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Safety and Efficacy of Non-Prescription (OTC) Analgesics and NSAIDs - Proceedings of the International Conference held at The South San Francisco Conference Center, San Francisco, CA, USA on Monday 17th March 1997 (Paperback, Softcover reprint of the original 1st ed. 1998)
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The availability of analgesics and non-steroidal anti-inflammatory
drugs (NSAIDs) sold over-the-counter (OTC) to the public without
prescription has become an issue of major concern in recent years.
The problem has been highlighted in the UK, USA and other countries
because of the continuing high rates of cases of poisoning and the
influence of switching from prescription-only status for many
NSAIDs to OTC sale brought about, in a large part, by governments
and health maintenance organisations (especially in the USA)
anxious to save on costs of these drugs. Concern in the UK about
poisoning from paracetamol and the appreciable morbidity and
mortality from aspirin was such that a major review was initiated
in 1996 by the UK government's Medicines Control Agency (MCA).
Doubtless, many other governments have also undertaken reviews of
the safety issues concerning OTC analgesics and NSAIDs. In the UK
the situation has culminated in the decision announced in August
1997, as this book was going to press, that the number of
tablets/capsules of the solid dosage forms of paracetamol and
aspirin would be limited for sale OTe. This decision was
essentially based on the need to limit the unit quantity of these
drugs so as to reduce the likelihood of poisoning with paracetamol
and the development of gastrointestinal and other more serious
side-effects from aspirin. Time. will tell whether these new
regulations will influence the occurrence of these adverse events.
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