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G Protein-Coupled Receptors in Drug Discovery (Paperback)
Loot Price: R1,970
Discovery Miles 19 700
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G Protein-Coupled Receptors in Drug Discovery (Paperback)
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The broad range of G protein-coupled receptors (GPCRs) encompasses
all areas of modern medicine and have an enormous impact on the
process of drug development. Using disease-oriented methods to
cover everything from screening to expression and crystallization,
G Protein-Coupled Receptors in Drug Discovery describes the
physiological roles of GPCRs and their involvement in various human
diseases. The book presents current approaches in drug discovery
that include target selection, establishment of screening and
functional assays. It also covers recombinant GPCR expression for
drug screening and structural biology, different methods for
structural characterization of GPCRs, and the importance of
bioinformatics. The book has been carefully edited to avoid
overlapping information, some duplication has been intentionally
permitted so that each chapter can function as an independent unit.
Providing in-depth discussions on structure and dynamics of GPCRs,
this book outlines the importance of the GPCRs to drug discovery in
general and drug targets specifically. Daniel E. Levy, editor of
the Drug Discovery Series, is the founder of DEL BioPharma, a
consulting service for drug discovery programs. He also maintains a
blog that explores organic chemistry.
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