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Books > Medicine > Pre-clinical medicine: basic sciences > Physiology
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Cilia and Nervous System Development and Function (Hardcover, 2013 ed.)
Loot Price: R5,693
Discovery Miles 56 930
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Cilia and Nervous System Development and Function (Hardcover, 2013 ed.)
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Cilia are tiny microtubule-based organelles projecting from the
plasma membrane of practically all cells in the body. In the past
10 years a flurry of research has indicated a crucial role of this
long-neglected organelle in the development and function of the
central nervous system. A common theme of these studies is the
critical dependency of signal transduction of the Sonic hedgehog,
and more recently, Wnt signaling pathways upon cilia to regulate
fate decisions and morphogenesis. Both primary and motile cilia
also play crucial roles in the function of the nervous system,
including the primary processing of sensory information, the
control of body mass, and higher functions such as behavior and
cognition, serving as "antennae" for neurons to sense and process
their environment. In this book we describe the structure and
function of cilia and the various tissues throughout the brain and
spinal cord that are dependent upon cilia for their proper
development and function.
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