Cardiovascular Disease - Molecular and Cellular Mechanisms, Prevention, and Treatment (Paperback, Softcover reprint of the original 1st ed. 1987)

The Sixth Annual International Spring Symposium on Health Sciences, held in Washington, D. C., in May 1986, brought together over 650 scientists from 19 countries to review and update research on cardiovascular disease. In this volume, which contains 59 chapters, an internationally recognized group of authors con tribute up-to-date accounts of molecular and cellular processes occurring in the vessel wall in atherogenesis and describe approaches to the prevention and treatment of atherosclerosis. The volume is divided into six major sections. Two sections deal with current aspects of lipoprotein metabolism. In Part I, we are alerted to the impact on li poprotein metabolism of structural heterogeneity within the four broad lipoprotein classes. Attention then turns to the components that orchestrate lipoprotein metab olism. Apolipoprotein identities, processing, and functions are described, as are the roles of lipid transfer proteins in plasma lipoprotein remodeling. Hepatic lipase synthesis and secretion are described. In Part II, Nobel Laureates Michael S. Brown and Joseph L. Goldstein describe mutations in the LDL receptor that reveal the functions of its various domains and point out how understanding the LDL receptor has provided a rational basis for its regulation. A discussion of the role of receptors in regulating cholesterol uptake by tissues follows, with emphasis on receptor-ligand interactions. Additional pathways for cholesterol delivery to cells are explored, as are pathways for cholesterol egress."

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	Gwumc Department of Biochemistry and Molecular Biology Annual Spring Symposia
Release date:	May 2012
First published:	May 2012
Editors:	Linda L. Gallo
Dimensions:	229 x 152 x 31mm (L x W x T)
Format:	Paperback
Pages:	608
Edition:	Softcover reprint of the original 1st ed. 1987
ISBN-13:	978-1-4684-5298-3
Categories:	Books > Medicine > Clinical & internal medicine > Cardiovascular medicine Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN:	1-4684-5298-3
Barcode:	9781468452983

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