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Books > Science & Mathematics > Biology, life sciences > Molecular biology
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RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay, Volume 448 (Hardcover)
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RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay, Volume 448 (Hardcover)
Series: Methods in Enzymology
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Specific complexes of protein and RNA carry out many essential
biological functions, including RNA processing, RNA turnover, RNA
folding, as well as the translation of genetic information from
mRNA into protein sequences. Messenger RNA (mRNA) decay is now
emerging as an important control point and a major contributor to
gene expression. Continuing identification of the protein factors
and cofactors, and mRNA instability elements, responsible for mRNA
decay allow researchers to build a comprehensive picture of the
highly orchestrated processes involved in mRNA decay and its
regulation.
The control of biological processes, such as cellular growth and
differentiation, is dependent on how the genetic material within a
cell is expressed. The cellular physiology of mRNA-including mRNA
processing, transport, localization, and turnover-is central to the
process of gene expression.
Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance
pathway.
Expert researchers introduce the most advanced technologies and
techniques to identify mRNA processing, transport, localization and
turnover which are central to the process of gene expression.
Offers step-by-step lab instructions including necessary equipment
and reagents
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