Since the interest on the thymus as an organ essential for the
development of immunological capacity was renewed more than ten
years ago, the search for a better understanding of the mecha-
nisms underlying its functions has not come to an end. Although the
first observations suggesting a link between the thymus and
immunocompetence related to certain clinical disorders in man such
as thymoma or Swiss type of agammaglobulinemia, the bulk of
evidence demonstrating the role of this lymphoepithelial organ in
immune reactivity originates from experimental work as ini- tiated
by Dr. MILLER and Dr. Goon's group. The full significance of the
thymic system is now beginning to unfold. The basic question to be
answered by the many investigators in the field is no longer
whether the thymus does in fact play the role of an immunologically
important organ but rather how it acts. In addition we need to know
in what period(s) of ontogenesis is a proper development of the
thymus a prerequisit for the buildup of an efficient peripheral
lymphoreticular system throughout the organism. Perinatal
thymectomy proved to be a valuable experimental approach to gain a
better insight into thymic functions. At first it looked as if this
measure, in most of the species tested, would largely depress or
abolish all immune reactions of the animal and lead to an
inescapable wasting syndrome within a few months.
General
| Imprint: |
Springer-Verlag
|
| Country of origin: |
Germany |
| Series: |
Experimentelle Medizin, Pathologie und Klinik, 25 |
| Release date: |
July 2012 |
| First published: |
1968 |
| Authors: |
M. W. Hess
|
| Dimensions: |
235 x 155 x 6mm (L x W x T) |
| Format: |
Paperback
|
| Pages: |
108 |
| Edition: |
Softcover reprint of the original 1st ed. 1968 |
| ISBN-13: |
978-3-642-86676-0 |
| Languages: |
German
|
| Categories: |
Books >
Medicine >
General issues >
General
Promotions
|
| LSN: |
3-642-86676-X |
| Barcode: |
9783642866760 |
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