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Endothelial Modulation of Cardiac Function (Hardcover)
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Endothelial Modulation of Cardiac Function (Hardcover)
Series: Endothelial Cell Research Series
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Paracrine and autocrine regulation of cardiac function by
"endothelial" mediators is becoming important both physiologically
and pathophysiologically. This volume brings the researcher
completely up to date with all aspects of endothelial regulation
and cardiac function. Acknowledged experts in each field have
contributed, making this work indispensable for researchers and of
great interest to the clinical cardiologist.
The Endothelial Cell Research Series publishes significant reviews
by experts in the field. The individual volumes provide invaluable
guides to researchers studying endothelial cells and are effective
reference texts for anyone working in the general areas of vascular
biology and neurotransmission.
Endothelium was originally considered to be an inert lining for the
blood vessels, but during the last fifteen years, this view has had
to be completely revised. It is now accepted that the endothelium
plays an important role in many diverse functions. This volume
concentrates on the effect of the endothelium on cardiac function.
It has been widely demonstrated that the endothelium exerts a
paracrine influence on contraction of adjacent cardiac muscle
through the release of several mediators, such as endothelin and
nitric oxide. Recent studies also show that the effects of such
mediators upon the heart are not limited to contraction alone.
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