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Books > Medicine > Nursing & ancillary services > Biomedical engineering
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Quantitative MRI of the Brain - Principles of Physical Measurement, Second edition (Paperback, 2nd edition)
Loot Price: R1,512
Discovery Miles 15 120
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Quantitative MRI of the Brain - Principles of Physical Measurement, Second edition (Paperback, 2nd edition)
Series: Series in Medical Physics and Biomedical Engineering
Expected to ship within 9 - 17 working days
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Building on the success of the first edition of this book, the
winner of the 2004 British Medical Association Radiology Medical
Book Competition, Quantitative MRI of the Brain: Principles of
Physical Measurement gives a unique view on how to use an MRI
machine in a new way. Used as a scientific instrument it can make
measurements of a myriad of physical and biological quantities in
the human brain and body. For each small tissue voxel, non-invasive
information monitors how tissue changes with disease and responds
to treatment. The book opens with a detailed exposition of the
principles of good practice in quantification, including
fundamental concepts, quality assurance, MR data collection and
analysis and improved study statistical power through minimised
instrumental variation. There follow chapters on 14 specific groups
of quantities: proton density, T1, T2, T2*, diffusion, advanced
diffusion, magnetisation transfer, CEST, 1H and multi-nuclear
spectroscopy, DCE-MRI, quantitative fMRI, arterial spin-labelling
and image analysis, and finally a chapter on the future of
quantification. The physical principles behind each quantity are
stated, followed by its biological significance. Practical
techniques for measurement are given, along with pitfalls and
examples of clinical applications. This second edition of this
indispensable 'how to' manual of quantitative MR shows the MRI
physicist and research clinician how to implement these techniques
on an MRI scanner to understand more about the biological processes
in the patient and physiological changes in healthy controls.
Although focussed on the brain, most techniques are applicable to
characterising tissue in the whole body. This book is essential
reading for anyone who wants to use the gamut of modern
quantitative MRI methods to measure the effects of disease, its
progression, and its response to treatment. Features: The first
edition was awarded the book prize for Radiology by the British
Medical Association in 2004 Written by an authority in the field:
Professor Tofts has an international reputation for quantification
in MRI Gives specific 'how to' information for implementation of
MRI measurement sequence techniques
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