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Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology

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Down Syndrome: From Understanding the Neurobiology to Therapy, Volume 197 (Hardcover, New) Loot Price: R4,076
Discovery Miles 40 760
You Save: R328 (7%)
Down Syndrome: From Understanding the Neurobiology to Therapy, Volume 197 (Hardcover, New): Mara Dierssen, Rafael de la Torre...

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Down Syndrome: From Understanding the Neurobiology to Therapy, Volume 197 (Hardcover, New)

Mara Dierssen, Rafael de la Torre Fornell

Series: Progress in Brain Research

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List price R4,404 Loot Price R4,076 Discovery Miles 40 760 | Repayment Terms: R379 pm x 12* You Save R328 (7%)

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Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of this volume is of broad interest for the neuroscience community, because it tackles the concept of neurogenomics, that is, how the genome as a whole contributes to a neurodevelopmental cognitive disorders, such as DS, and thus to the development, structure and function of the nervous system.

This volume of Progress in Brain Research discusses comparative genomics, gene expression atlases of the brain, network genetics, engineered mouse models and applications to human and mouse behavioral and cognitive phenotypes. It brings together scientists of diverse backgrounds, by facilitating the integration of research directed at different levels of biological organization, and by highlighting translational research and the application of the existing scientific knowledge to develop improved DS treatments and cures.
Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future researchChapters are extensively referenced to provide readers with a comprehensive list of resources on the topics coveredAll chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

General

Imprint: Elsevier Science Ltd
Country of origin: United Kingdom
Series: Progress in Brain Research
Release date: May 2012
First published: July 2012
Volume editors: Mara Dierssen • Rafael de la Torre Fornell
Dimensions: 235 x 191mm (L x W)
Format: Hardcover
Pages: 272
Edition: New
ISBN-13: 978-0-444-54299-1
Categories: Books > Medicine > Clinical & internal medicine
Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology
Books > Academic & Education > Professional & Technical
Books > Academic & Education > Professional & Technical > Neuroscience
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LSN: 0-444-54299-X
Barcode: 9780444542991

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