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Microglia in Health and Disease (Paperback, Softcover reprint of the original 1st ed. 2014)
Loot Price: R5,977
Discovery Miles 59 770
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Microglia in Health and Disease (Paperback, Softcover reprint of the original 1st ed. 2014)
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These past few years have witnessed a revolution in our
understanding of microglia, especially since their roles in the
healthy central nervous system (CNS) have started to unravel. These
cells were shown to actively maintain health, in concert with
neurons and other types of CNS cells, providing further insight
into their involvement with diseases. Edited by two pioneers in the
field, Marie-Eve Tremblay and Amanda Sierra, Microglia in health
and disease aims to share with the broader scientific community
some of the recent discoveries in microglia research, from a broad
perspective, with a collection of 19 chapters from 52 specialists
working in 11 countries across 5 continents. To set microglia on
the stage, the book begins by explaining briefly who they are, what
they do in the healthy and diseased CNS, and how they can be
studied. The first section describes in more details their
physiological roles in the maturation, function, and plasticity of
the CNS, across development, adolescence, adulthood, neuropathic
pain, addiction, and aging. The second section focuses on their
implication in pathological conditions impairing the quality of
life: neurodevelopmental and neuropsychiatric disorders, AIDS, and
multiple sclerosis; and in leading causes of death: ischemia and
stroke, neurodegenerative diseases, as well as trauma and injury.
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