In recent decades, the use of neuroimaging techniques has
resulted in outstanding progress in the diagnosis and management of
neurological diseases, and this is particularly true of those
diseases that affect the white matter of the brain and spinal cord.
This book, written by internationally acclaimed experts, comprises
a series of comprehensive and up-to-date reviews on the use of MR
imaging in these major neurological conditions. The diverse
available MR techniques, such as magnetization transfer MRI,
diffusion-weighted MRI, MR spectroscopy, functional MRI,
cell-specific MRI, perfusion MRI, and microscopic imaging with
ultra-high field MRI, offer an extraordinarily powerful means of
gaining fundamental in vivo insights into disease processes. The
strengths and weaknesses of all these techniques in the study of
multiple sclerosis and other relevant diseases are extensively
considered. After an introductory section on neuroimaging
technology, subsequent sections address disorders of myelination,
demyelinating diseases, immune-mediated disorders, and white matter
disorders related to aging and other conditions. This book provides
a valuable summary of the state of the art in the field, and
defines important areas for future research.
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