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Scleroderma, An Issue of Rheumatic Disease Clinics, Volume 41-3 (Hardcover, UK ed.)
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Scleroderma, An Issue of Rheumatic Disease Clinics, Volume 41-3 (Hardcover, UK ed.)
Series: The Clinics: Internal Medicine
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Scleroderma, or systemic sclerosis, is a chronic connective tissue
disease generally classified as one of the autoimmune rheumatic
diseases. Hardening of the skin is one of the most visible
manifestations of the disease. It's estimated that about 300,000
Americans have scleroderma. About one third of those people have
the systemic form of scleroderma. Since scleroderma presents with
symptoms similar to other autoimmune diseases, diagnosis is
difficult. This issue will cover: The Genetic Basis of SSc:
Genetics, Epigenetics, Mechanisms of Pathogenesis - linking
fibrosis, vasculopathy and immune dysregulation, The Role of
Autoantibodies in Diagnosis and Prognosis/survival, Managing
Raynaud's phenomenon and ischemic ulcers Managing SSc Lung Disease,
Monitoring for and Managing Pulmonary Arterial Hypertension, and
many more!
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