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Books > Medicine > Nursing & ancillary services > Biomedical engineering
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Active Implants and Scaffolds for Tissue Regeneration (Paperback, 2011 ed.)
Loot Price: R4,296
Discovery Miles 42 960
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Active Implants and Scaffolds for Tissue Regeneration (Paperback, 2011 ed.)
Series: Studies in Mechanobiology, Tissue Engineering and Biomaterials, 8
Expected to ship within 10 - 15 working days
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Active implants are actually drug or protein-eluting implants that
induce healing effects, in addition to their regular task, such as
support. This effect is achieved by controlled release of the
active agent to the surrounding tissue. This book will give a broad
overview of biomaterial platforms used as basic elements of
drug-eluting implants. It will include mainly coatings for vascular
stents with controlled release of antiproliferative agents, wound
dressings with controlled release of antibacterial agents,
drug-eluting vascular grafts, protein-eluting scaffolds for tissue
regeneration, drug-eluting platforms for dental and other
applications. Thus, both internal and external implants are
described. The drug-eluting implants will be described in terms of
matrix formats and polymers, incorporated drugs and their release
profiles from the implants, as well as implant functioning. Smart
polymeric systems, such as crosslinked poly-lactones, thermo and
pH-sensitive hydrogels and poly(amido-amines), as well as novel
basic structural elements, such as composite fibers and films, and
nanostructures will be thoroughly described. The effect of the
processing parameters on the microstructure and on the resulting
drug release profiles, mechanical and physical properties, and
other relevant properties, will be emphasized. The described new
biomaterials approaches for active implants enhance the tools
available for creating clinically important biomedical
applications.
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