Books > Medicine > Clinical & internal medicine > Geriatric medicine
|
Buy Now
Research Progress in Alzheimer's Disease & Dementia - Volume 1 (Hardcover, Illustrated Ed)
Loot Price: R3,241
Discovery Miles 32 410
|
|
Research Progress in Alzheimer's Disease & Dementia - Volume 1 (Hardcover, Illustrated Ed)
Expected to ship within 12 - 17 working days
|
Alzheimer's disease (AD) is the most common type of
neurodegenerative disorder in the ageing population, with dementia
as a common consequence. AD is defined pathologically by the
appearance of extracellular senile plaques and intracellular
neurofibrillary tangles, as described by Alois Alzheimer about a
century ago. The causes for AD include genetic predisposition in a
small population, ageing and environmental stresses in majority
cases. The underlying pathogenic cascades, increases in expression
of amyloid precursor protein and accumulation of Ass and reactive
oxidant activity and inflammation, have the features of both
adaptive, at least initially, and harmful when becoming excessive.
Dementia, on the other hand, is a clinical diagnosis and is defined
as globally, persistently impaired cognitive skills including
memory. Alzheimer dementia refers to clinical dementia in patients
who also have Alzheimer neuropathology. Alzheimer dementia is what
brings the patients to seek medical treatments. An extraordinary
inability to form new memory, especially of those episodic type,
and executive dysfunction are among the earliest symptoms in AD
patients. In end-stage AD, cognitive degeneration extends far
beyond memory loss. The underlying causes include decreases in
impaired brain metabolism, which results in impaired synaptic
functions and capacities, thus impaired information processing, and
eventually leads to neuronal injury and death. This book presents
leading-edge research in this dynamic field.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.