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Systems Biology of Metabolic and Signaling Networks - Energy, Mass and Information Transfer (Paperback, Softcover reprint of the original 1st ed. 2014)
Loot Price: R5,631
Discovery Miles 56 310
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Systems Biology of Metabolic and Signaling Networks - Energy, Mass and Information Transfer (Paperback, Softcover reprint of the original 1st ed. 2014)
Series: Springer Series in Biophysics, 16
Expected to ship within 10 - 15 working days
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Total price: R5,651
Discovery Miles: 56 510
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Systems Biology represents a new paradigm aiming at a
whole-organism-level understanding of biological phenomena,
emphasizing interconnections and functional interrelationships
rather than component parts. The study of network properties, and
how they control and regulate behavior from the cellular to
organism level, constitutes a main focus of Systems Biology. This
book addresses from a novel perspective a major unsolved biological
problem: understanding how a cell works and what goes wrong in
pathology. The task undertaken by the authors is in equal parts
conceptual and methodological, integrative and analytical,
experimental and theoretical, qualitative and quantitative,
didactic and comprehensive. Essentially, they unravel the
spatio-temporal unfolding of interacting mass-energy and
information networks at the cellular and organ levels, as well as
its modulation through activation or repression by signaling
networks to produce a certain phenotype or (patho)physiological
response. Starting with the historical roots, in thirteen chapters
this work explores the Systems Biology of signaling networks,
cellular structures and fluxes, organ and microorganism functions.
In doing so, it establishes the basis of a 21st century approach to
biological complexity.
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