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Drug-Induced Liver Toxicity (Hardcover, 1st ed. 2018)
Loot Price: R3,939
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Drug-Induced Liver Toxicity (Hardcover, 1st ed. 2018)
Series: Methods in Pharmacology and Toxicology
Expected to ship within 10 - 15 working days
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This book provides a comprehensive view of the methodologies used
for the study of liver toxicity encountered throughout the whole
life cycle of a drug, from drug discovery, to clinical trial,
post-marketing, and even clinical practice. Organized into six
sections, the first section introduces the mechanisms contributing
to drug-induced liver toxicity. The second and third section
explore in silico and in vitro approaches used to help mitigate
hepatotoxicity liability at the early stages of drug development.
The fourth section describes methodologies applied in regulatory
processes, including preclinical studies, clinical trials, and
post-marketing surveillance. The fifth section discusses clinical
hepatotoxicity. Emerging technologies are examined in the final
section. As a volume in the Methods in Pharmacology and Toxicology
series, chapters include the kind of expert advice that will lead
to optimal results. Authoritative and practical, Drug-Induced Liver
Toxicity serves all those who aim to improve assessment and
understanding of hepatotoxic potentials of new medications and
marketed drugs. Chapter 30 is open access under a CC BY 4.0 license
via link.springer.com.
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