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Books > Medicine > Clinical & internal medicine > Medical diagnosis
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Molecular Diagnostics: Promises and Possibilities (Paperback, 2010 ed.)
Loot Price: R4,282
Discovery Miles 42 820
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Molecular Diagnostics: Promises and Possibilities (Paperback, 2010 ed.)
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A rapid development in diverse areas of molecular biology and
genetic engineering resulted in emergence of variety of tools.
These tools are not only applicable to basic researches being
carried out world over, but also exploited for precise detection of
abnormal conditions in plants, animals and human body. Although a
basic researcher is well versed with few techniques used by him/her
in the laboratory, they may not be well acquainted with
methodologies, which can be used to work out some of their own
research problems. The picture is more blurred when the molecular
diagnostic tools are to be used by physicians, scientists and
technicians working in diagnostic laboratories in hospitals,
industry and academic institutions. Since many of them are not
trained in basics of these methods, they come across several gray
areas in understanding of these tools. The accurate application of
molecular diagnostic tools demands in depth understanding of the
methodology for precise detection of the abnormal condition of
living body. To meet the requirements of a good book on molecular
diagnostics of students, physicians, scientists working in
agricultural, veterinary, medical and pharmaceutical sciences, it
needs to expose the reader lucidly to: Give basic science behind
commonly used tools in diagnostics Expose the readers to detailed
applications of these tools and Make them aware the availability of
such diagnostic tools The book will attract additional audience of
pathologists, medical microbiologists, pharmaceutical sciences,
agricultural scientists and veterinary doctors if the following
topics are incorporated at appropriate places in Unit II or
separately as a part of Unit-III in the book. Molecular diagnosis
of diseases in agricultural crops Molecular diagnosis of veterinary
diseases. Molecular epidemiology, which helps to differentiate
various epidemic strains and sources of disease outbreaks. Even in
different units of the same hospital, the infections could be by
different strains of the same species and the information becomes
valuable for infection control strategies. Drug resistance is a
growing problem for bacterial, fungal and parasitic microbes and
the molecular biology tools can help to detect the drug resistance
genes without the cultivation and in vitro sensitivity testing.
Molecular diagnostics offers faster help in the selection of the
proper antibiotic for the treatment of tuberculosis, which is a
major problem of the in the developing world. The conventional
culture and drug sensitivity testing of tuberculosis bacilli is
laborious and time consuming, whereas molecular diagnosis offers
rapid drug resistant gene detection even from direct clinical
samples. The same approach for HIV, malaria and many more diseases
needs to be considered. Molecular diagnostics in the detection of
diseases during foetal life is an upcoming area in the foetal
medicine in case of genetic abnormalities and infectious like TORCH
complex etc. The book will be equally useful to students,
scientists and professionals working in the field of molecular
diagnostics.
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