MicroRNAs as Tools in Biopharmaceutical Production (Paperback, 2012 ed.)

Focused manuscript on the potential use/role of miRNAs in bioprocessing, specifically the production of complex proteins in mammalian cells. With that in mind I propose a draft list of topics/chapters along the following lines: Intro on CHO/bioprocessing/engineering challenges to set scene, Genomic organization, biogenesis and mode of action, Identifying miRNA targets: Computational prediction, transcriptomics, proteomices, UTR analysis, etc., miRNA expression in Chinese Hamster Ovary cells, miRNAs as engineering targets: pathway manipulation to impact bioprocess phenotypes, miRNAs as biomarkers, Detection methods: Northern, PCR, hybridization arrays, Next Gen Seq, Manipulation of expression in cultured cells: Transient/stable disregulation, Knockout.

General

Imprint:	Springer
Country of origin:	Netherlands
Release date:	December 2014
Editors:	Niall Barron
Dimensions:	235 x 155 x 7mm (L x W x T)
Format:	Paperback
Pages:	126
Edition:	2012 ed.
ISBN-13:	978-9400795266
Categories:	Books > Professional & Technical > Biochemical engineering > Biotechnology > Genetic engineering Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
LSN:	9400795262
Barcode:	9789400795266

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