Cell biology is a rapidly advancing subject. Understanding
principles of nuclear architecture is a key question. Researchers
are starting to develop more strict and rigorous methods of image
processing and quantitative analysis to provide an end-to-end
process supporting the fundamental biology.
This book has chapters contributed by experts in the field that
address the whole endeavour of teasing out the principles of
nuclear architecture: ranging from fundamental science, through
imaging processing and quantitative analysis, to applications,
related to disease. This material is focussed on the latest
breakthroughs, and moreover will emphasise a strict and rigorous
development of the scientific process. A systems view is stressed
where relevant. The objective is not to provide an encyclopaedic
compendium of nuclear architecture information, but rather to
present state of the art tools in specific contexts, which will
readily generalise.
General
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