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Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
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Epigenetic Methods in Neuroscience Research (Hardcover, 1st ed. 2016)
Loot Price: R2,760
Discovery Miles 27 600
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Epigenetic Methods in Neuroscience Research (Hardcover, 1st ed. 2016)
Series: Neuromethods, 105
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This volume presents state-of-the-art methods for reliable
detection of epigenetic changes in the nervous system. Epigenetic
Methods in Neuroscience Research guides readers through methods for
the analyses of chromatin remodeling, transposable elements,
non-coding RNAs, such as miRNAs, and circadian oscillations,
including: analysis of DNA methylation in neuronal and glial cells
or small tissue samples; sensitive method for quantification of
alternative methylated forms of cytosines by liquid
chromatography/mass spectrometry; affinity-based detection of
modified cytosines by immunohistochemistry or methylated DNA
immunoprecipitation; chromatin immunoprecipitation, or ChIP; miRNA
high-throughput profiling and the in situ detection of miRNA subtle
expression in the brain; analysis of genes with alternative 3'UTRs;
and the cite-specific delivery of chromatin-modifying drugs.
Written in the popular Neuromethods series style, chapters include
the kind of detail and key advice from the specialists needed to
get successful results in your own laboratory. Concise and
easy-to-use, Epigenetic Methods in Neuroscience Research provides
multidisciplinary epigenetic approach to study genome, and neural,
plasticity that will help the reader to successfully address the
challenges associated with neurodevelopmental, psychiatric, and
neurodegenerative disorders.
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