The examination of structure at the microscopic scale, between
micrometers and angstrom units, has changed dramatically in recent
decades. Many new types of microscopy have emerged, notably the
many scanning-probe designs, some of which also allow manipulation
of atoms to form wanted structures, while others now permit direct
observation of moving proteins in liquids. The traditional electron
microscope is being revolutionized by the arrival of aberration
correctors and monochromators, which bring the resolution below the
Angstrom and electron-volt level. The "laboratory in a microscope"
concept is rapidly evolving, as nanostructures are observed forming
under controlled conditions at atomic resolution (the carbon
nanotube being the most famous recent example). Electron holography
and scanning transmission electron microscopy have become
indispensable tools of the semiconductor industry. The oldest form
of microscopy, optical microscopy, has been rejuvenated by the
development of fluorescent, confocal, and two-photon variants.
Analytical Scanning X-ray microscopes and Photoemission microscopes
at synchrotons now routinely provide spatially resolved electronic
structure maps. Tomographic imaging has vastly increased the
information content of practically all forms of microscopy, as
reflected in the award of a recent Nobel Prize. Molecular biology
is benefiting enormously from progress in this technique. Most of
these developments are responses to the urgent needs of researchers
to characterize new useful nanostructures at the atomic level.
In "Science of Microscopy," comprehensive reviews set these
innovations in the context of microscopy today. Each contribution
presents a form of microscopy or occasionally a microscopic
technique, and provides information about the instruments involved
and their areas of application. The contributions are written in
such a way that the reader can understand how the various
instruments function, their strengths and weaknesses, and whether
they are suitable for a particular scientific investigation.
Science of Microscopy will be an indispensable guide to both a wide
range of scientists in university laboratories and to engineers and
scientists in industrial R&D departments.
Key FeaturesFull-length essays on each type of instrument or
techniqueApplications to both materials science and thebiomedical
sciencesEssay-length treatmentby respected experts in each
fieldCovers the latest developments as well as background
information for the beginning microscopist"
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