Stroke is a global health problem affecting approximately 15
million people annually in the world and about 700,000 in the
United States. It is the third leading cause of death and the most
common cause of disability in most developed countries.
Acute Ischemic Injury and Repair in the Nervous System is
intended to provide the most up-to-date knowledge of the mechanisms
of neuronal death and repair after stroke. It is our belief that
this volume of the Handbook of Neurochemistry and Molecular
Neurobiology provides an excellent review of the tremendous
advances of the past decades in the neurochemical and molecular
biological aspects of cerebral ischemia. It is hoped that these
advances will provide an impetus for basic scientists and
clinicians to further their translational research and to promote
the insights for development of therapeutic interventions for
stroke.
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