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Animal Models of Schizophrenia and Related Disorders (Paperback, Softcover reprint of the original 1st ed. 2011)
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Animal Models of Schizophrenia and Related Disorders (Paperback, Softcover reprint of the original 1st ed. 2011)
Series: Neuromethods, 59
Expected to ship within 10 - 15 working days
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Animal models of schizophrenia and other major psychiatric
disorders have been sought for decades, and, as a result, we are
now facing new vistas on pathophysiology that could lead to novel
therapeutic approaches and even hint at possible preventive
strategies. Animal Models of Schizophrenia and Related Disorders
presents an overview of the information that can be obtained with
several different models and a detailed account of how to generate
such models in order to ensure that the manipulations used to model
schizophrenia-relevant phenomena are used consistently across
laboratories. This detailed volume features pharmacological models
such as non-competing NMDA antagonists, emphasizing their use in
vitro, neurodevelopmental models such as the neonatal ventral
hippocampal lesion and the antimitotic MAM, models that reproduce
environmental factors such as neonatal hypoxia, vitamin D deficits,
and prenatal immune activation, as well as several different
genetic model approaches. As a volume in the Neuromethods series,
this volume contains the kind of detailed description and
implementation advice that is crucial for getting optimal results.
Practical and cutting-edge, Animal Models of Schizophrenia and
Related Disorders highlights the successes in the use of animal
models to gain insight on pathophysiological mechanisms of
relevance to major psychiatric disorders in the hope of inspiring
investigators to expand the research and test targets that could
restore or ameliorate function.
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