The endocannabinoid system consists of cannabinoid receptors, their
endogenous lipid ligands (endocannabinoids) and the enzymatic
machinery for their synthesis and degradation. In the brain,
endocannabinoids regulate ion channel activity and neurotransmitter
release and thereby contribute to various aspects of brain
function, including memory, reward and emotions. Their ability to
modulate synaptic efficacy has a wide range of functional
consequences and provides unique therapeutic possibilities.
Unprecedented advances have been made in the understanding of the
role of endocannabinoids in the regulation of the emotional brain
over the past few years. However, a comprehensive book encompassing
all these aspects is still lacking. The book will provide an
overview of the role played by the endocannabinoid system in the
regulation of emotional processes with particular emphasis on the
modulation of memory and reward for emotionally arousing events and
for the regulation of motivational aspects in cannabis use.
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