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Books > Science & Mathematics > Biology, life sciences > Molecular biology
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Between Nucleus and Cytoplasm (Hardcover, 1991 ed.)
Loot Price: R5,641
Discovery Miles 56 410
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Between Nucleus and Cytoplasm (Hardcover, 1991 ed.)
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In the last decade nucleo-cytoplasmic transport has developed into
one of the most active areas of research in cell biology and its
significance for cell biology as a whole has been recognized. It
has led to elucidation of the mechanisms of major cellular
functions such as protein synthesis and cellular differentiation.
It is also helping to bring about a synthesis of ultrastructural,
biochemical, molecular biological and biophysical approaches to the
study of cellular organization and function. These theoretical
advances have been made possible chiefly by advances in technology
- improved methods of gene manipulation and sequencing, of
monoclonal antibody production and the use of protein chemistry, of
microscopy and of cell manipulation, including microinjection
methods. Developments in molecular biology, such as the search for
sequence - specific DNA binding proteins and the identification of
their binding domains, have also furthered advances in cell biology
and these areas have become increasingly integrated with some
well-established areas of biochemistry. This book aims to be an
introduction, for senior undergraduates and postgraduate
biologists, to the field of nucleo-cytoplasmic transport and its
relevance to cell biology and seeks to use recent advances in the
field to illustrate the process by which modern scientific progress
occurs - the importance of developing techniques for formulating
problems as well as answering them and the integration of different
approaches leading to the evolution of novel concepts. The author
assumes a basic general knowledge of molecular and cell biology and
of biochemistry, but provides all the necessary background for
discussion of recent advances and in the final chapters discusses
the actual and potential contributions of the field of
nucleo-cytoplasmic transport to cell biology.
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