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Books > Science & Mathematics > Biology, life sciences > Molecular biology
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Life's Ratchet - How Molecular Machines Extract Order from Chaos (Hardcover)
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Life's Ratchet - How Molecular Machines Extract Order from Chaos (Hardcover)
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Life is an enduring mystery. Yet, science tells us that living
beings are merely sophisticated structures of lifeless molecules.
If this view is correct, where do the seemingly purposeful motions
of cells and organisms originate? In Life's Ratchet , physicist
Peter M. Hoffmann locates the answer to this age-old question at
the nanoscale.Below the calm, ordered exterior of a living organism
lies microscopic chaos, or what Hoffmann calls the molecular
storm,specialized molecules immersed in a whirlwind of colliding
water molecules. Our cells are filled with molecular machines,
which, like tiny ratchets, transform random motion into ordered
activity, and create the purpose" that is the hallmark of life.
Tiny electrical motors turn electrical voltage into motion,
nanoscale factories custom-build other molecular machines, and
mechanical machines twist, untwist, separate and package strands of
DNA. The cell is like a city,an unfathomable, complex collection of
molecular workers working together to create something greater than
themselves.Life, Hoffman argues, emerges from the random motions of
atoms filtered through these sophisticated structures of our
evolved machinery. We are agglomerations of interacting nanoscale
machines more amazing than anything in science fiction. Rather than
relying on some mysterious life force" to drive them,as people
believed for centuries,life's ratchets harness instead the second
law of thermodynamics and the disorder of the molecular
storm.Grounded in Hoffmann's own cutting-edge research, Life's
Ratchet reveals the incredible findings of modern nanotechnology to
tell the story of how the noisy world of atoms gives rise to life
itself.
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