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Endogenous Toxins - Targets for Disease Treatment and Prevention 2 Volume Set (Hardcover)
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Endogenous Toxins - Targets for Disease Treatment and Prevention 2 Volume Set (Hardcover)
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Designed as a first-stop reference for researchers and
professionals in toxicology, pharmacology and medicine, this
handbook is the very first to tie together the knowledge from many
disciplines that has so far been available only from widely
dispersed sources in the primary literature. As such, it presents
the complete picture on what is currently known about endogenous
toxins, including their generation, mode of action, resulting
disease condition, and available countermeasures.
Clearly divided into four parts, the first systematically covers
important toxic molecule species, including metabolic intermediates
and reactive oxygen species. The second discusses the role of
genetically determined metabolic malfunctions, such as
galactosemia, hyperlipidemia, porphyria, hemochromatosis and
related conditions, while part three looks at acquired and chronic
diseases caused or exacerbated by endogenous toxins, such as
hepatic injury, asthma, rheumatism, colorectal cancer, reperfusion
diseases, neurodegneration and aging. The final part reviews
currents strategies to control and minimize the effect of
endogenous toxins, either by nutritional or pharmacological
interventions.
With its complete coverage integrating molecular and systemic
aspects from the biochemical basis to human disease conditions,
this comprehensive reference will appeal to a broad target group of
toxicologists, biochemists, nutrition specialists and physicians.
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