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Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > Vertebrates > Mammals
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Sigma Receptors, Volume 12 (Hardcover)
Loot Price: R3,445
Discovery Miles 34 450
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Sigma Receptors, Volume 12 (Hardcover)
Series: Neuroscience Perspectives
Expected to ship within 10 - 15 working days
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Neuroscience Perspectives provides multidisciplinary reviews of
topics in one of the most diverse and rapidly advancing fields in
the life sciences. Whether you are a new recruit to neuroscience,
or an established expert, look to this series for 'one-stop'
sources of the historical, physiological, pharmacological,
biochemical, molecular biological and therapeutic aspects of chosen
research areas. The sigma receptor was originally thought to be a
subset of the opioid receptor family, and it is less than 10 years
since it was recognized that this receptor represents unique
binding sites in mammalian brain and peripheral organs, distinct
from any other known neurotransmitter receptor. Since the sigma
receptors exhibit high affinity for members of diverse classes of
psychotropic drugs, and have been postulated to be involved in
various central nervous disorders, neuroscientists have
demonstrated a great deal of interest in the elucidation of these
receptor sites and their biological relevance. Relatively little is
known about the precise role of sigma receptors in normal brain
function and in CNS disorders, despite an overwhelming research
effort. This research has resulted in many controversies, some of
which have been reconciled while others have not. This volume aims
to update the reader on the current situation, and deals with the
potential functional significance of these receptors in the brain
and peripheral organs and, where appropriate, makes reference to
the clinical potential of these sites.
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