Posttranslational Protein Modifications in the Reproductive System (Hardcover, 2014 ed.)

Capacitation is defined as the ensemble of modifications that render ejaculated sperm competent to fertilize, either in the female tract or in vitro. Capacitation can occur spontaneously in vitro in defined media, suggesting it is intrinsically regulated and, once initiated, follows a pre-programmed pathway. Unlike other signaling cascades, capacitation is unique as it occurs without a specific ligand. The authors show how the sperm, a highly compartmentalised and non-transcriptional cell, undergoes the complexities of capacitation. The acrosome reaction remains unclear. The book also features chapters on sperm-egg binding, as well as on histone modification in both the embryo and sperm. Chapters are devoted to protein ubiquitination, the regulation of sperm function during fertilization in mammals, and tubulin modifications in gametes and embryos. There are no other current books on post-translational protein modifications as they relate to reproduction, and this book is unique in the field. It is useful for both researchers and graduate students alike.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	Advances in Experimental Medicine and Biology, 759
Release date:	July 2014
First published:	2014
Editors:	Peter Sutovsky
Dimensions:	235 x 155 x 16mm (L x W x T)
Format:	Hardcover
Pages:	249
Edition:	2014 ed.
ISBN-13:	978-1-4939-0816-5
Categories:	Books > Medicine > General issues > Medical equipment & techniques > Medical research Books > Medicine > Clinical & internal medicine > Endocrinology > General
LSN:	1-4939-0816-2
Barcode:	9781493908165

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