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Posttranslational Protein Modifications in the Reproductive System (Hardcover, 2014 ed.)
Loot Price: R4,114
Discovery Miles 41 140
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Posttranslational Protein Modifications in the Reproductive System (Hardcover, 2014 ed.)
Series: Advances in Experimental Medicine and Biology, 759
Expected to ship within 10 - 15 working days
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Capacitation is defined as the ensemble of modifications that
render ejaculated sperm competent to fertilize, either in the
female tract or in vitro. Capacitation can occur spontaneously in
vitro in defined media, suggesting it is intrinsically regulated
and, once initiated, follows a pre-programmed pathway. Unlike other
signaling cascades, capacitation is unique as it occurs without a
specific ligand. The authors show how the sperm, a highly
compartmentalised and non-transcriptional cell, undergoes the
complexities of capacitation. The acrosome reaction remains
unclear. The book also features chapters on sperm-egg binding, as
well as on histone modification in both the embryo and sperm.
Chapters are devoted to protein ubiquitination, the regulation of
sperm function during fertilization in mammals, and tubulin
modifications in gametes and embryos. There are no other current
books on post-translational protein modifications as they relate to
reproduction, and this book is unique in the field. It is useful
for both researchers and graduate students alike.
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