Over the last few years remarkable progress has been
accomplished with respect to our understanding of nuclear structure
and trafficking. This volume concentrates on aspects that involve
or are of relevance to RNA and RNPs. Topics include fundamental
advances and current problems in the structural organization of
different subnuclear compartments: chromatin, nucleolus and
perinucleolar compartment, Cajal bodies and gems, speckles
containing splicing factors, as well as the PML bodies
characteristic of ProMyelocytic Leukemia. It also describes recent
progress in the dynamic aspects of RNA trafficking and in the
latest technologies for live cell imaging of mRNA. The major
general message of this volume is that nuclear structure is much
more dynamic than previously anticipated.
General
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