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Oligonucleotide Synthesis - Methods and Applications (Hardcover, 2005 ed.) Loot Price: R5,167
Discovery Miles 51 670
Repayment Terms: R484 pm x 12*
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Oligonucleotide Synthesis - Methods and Applications (Hardcover, 2005 ed.): Piet Herdewijn

Oligonucleotide Synthesis - Methods and Applications (Hardcover, 2005 ed.)

Piet Herdewijn

Series: Methods in Molecular Biology, 288

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Loot Price R5,167 Discovery Miles 51 670 | Repayment Terms: R484 pm x 12*

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A collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation. The applications include using molecular beacons to monitor the PCR amplification process, nuclease footprinting to study the sequence-selective binding of small molecules of DNA, nucleic acid libraries, and the use of small interference RNA (siRNA) as an inhibitor of gene expression.

General

Imprint: HumanaPress
Country of origin: United States
Series: Methods in Molecular Biology, 288
Release date: September 2004
First published: 2005
Editors: Piet Herdewijn
Dimensions: 235 x 155 x 25mm (L x W x T)
Format: Hardcover
Pages: 436
Edition: 2005 ed.
ISBN-13: 978-1-58829-233-9
Categories: Books > Medicine > Clinical & internal medicine > General
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LSN: 1-58829-233-9
Barcode: 9781588292339

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