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Oligonucleotide Synthesis - Methods and Applications (Hardcover, 2005 ed.) Loot Price: R5,160

Discovery Miles 51 600

Repayment Terms: R484 pm x 12*

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Oligonucleotide Synthesis - Methods and Applications (Hardcover, 2005 ed.): Piet Herdewijn

Oligonucleotide Synthesis - Methods and Applications (Hardcover, 2005 ed.)

Piet Herdewijn

Series: Methods in Molecular Biology, 288

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Loot Price R5,160 Discovery Miles 51 600 | Repayment Terms: R484 pm x 12*

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A collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation. The applications include using molecular beacons to monitor the PCR amplification process, nuclease footprinting to study the sequence-selective binding of small molecules of DNA, nucleic acid libraries, and the use of small interference RNA (siRNA) as an inhibitor of gene expression.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 288
Release date:	September 2004
First published:	2005
Editors:	Piet Herdewijn
Dimensions:	235 x 155 x 25mm (L x W x T)
Format:	Hardcover
Pages:	436
Edition:	2005 ed.
ISBN-13:	978-1-58829-233-9
Categories:	Books > Medicine > Clinical & internal medicine > General Promotions
LSN:	1-58829-233-9
Barcode:	9781588292339