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Quantitative Methods for Investigating Infectious Disease Outbreaks (Paperback, 1st ed. 2019)
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Quantitative Methods for Investigating Infectious Disease Outbreaks (Paperback, 1st ed. 2019)
Series: Texts in Applied Mathematics, 70
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This book provides a systematic treatment of the mathematical
underpinnings of work in the theory of outbreak dynamics and their
control, covering balanced perspectives between theory and practice
including new material on contemporary topics in the field of
infectious disease modelling. Specifically, it presents a unified
mathematical framework linked to the distribution theory of
non-negative random variables; the many examples used in the text,
are introduced and discussed in light of theoretical perspectives.
The book is organized into 9 chapters: The first motivates the
presentation of the material on subsequent chapters; Chapter 2-3
provides a review of basic concepts of probability and statistical
models for the distributions of continuous lifetime data and the
distributions of random counts and counting processes, which are
linked to phenomenological models. Chapters 4 focuses on dynamic
behaviors of a disease outbreak during the initial phase while
Chapters 5-6 broadly cover compartment models to investigate the
consequences of epidemics as the outbreak moves beyond the initial
phase. Chapter 7 provides a transition between mostly theoretical
topics in earlier chapters and Chapters 8 and 9 where the focus is
on the data generating processes and statistical issues of fitting
models to data as well as specific mathematical epidemic modeling
applications, respectively. This book is aimed at a wide audience
ranging from graduate students to established scientists from
quantitatively-oriented fields of epidemiology, mathematics and
statistics. The numerous examples and illustrations make
understanding of the mathematics of disease transmission and
control accessible. Furthermore, the examples and exercises, make
the book suitable for motivated students in applied mathematics,
either through a lecture course, or through self-study. This text
could be used in graduate schools or special summer schools
covering research problems in mathematical biology.
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