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Connective Tissues - Biochemistry and Pathophysiology (Paperback, Softcover reprint of the original 1st ed. 1974)
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Connective Tissues - Biochemistry and Pathophysiology (Paperback, Softcover reprint of the original 1st ed. 1974)
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connective tissues are essential for the physical functioning of
the animals's body. The condition of the various connective tissues
is governed by biochemical factors, anabolism and catabolism, that
are controlled by specific enzymes. Any change outside the normal
range of metabolism, for instance induced by immunological
reactions, may induce a pathological disturbance. The result can be
acute or chronic inflammation, or loss of normal function,
expressed in loosening, dilatation, breaking, wear, stiffness,
shrinking, scars, stenosis, and cirrhosis or any other kind of
fibrosis. A first step toward improving our understanding of the
feedback mecha nism that maintains the biological status and
texture of a given connective tissue is to combine what is known
about synthesis and enzymatic degradation of the components of
fibers and ground substance. Common pathological phenomena like
chronic inflammation of immune reactions can be either the result
of the cause of disturbances in the sensitive balance of connective
tissue metabolism. Nowadays con nective tissues are less and less
regarded as brady trophic tissue but rather as a stimulating and
many-sided problem of research. Before we can understand the
pathogenesis of the connective tissue diseases that result in the
destructive processes mentioned above, basic research will be
necessary. This research will be furthered by a constant exchange
of information and the results of. observations. To promote this
exchange of information between scientists, symposia on connective
tissue research are organized at regular intervals."
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