Fundamentals of Analytical Toxicology is an integrated introduction
to the analysis of drugs, poisons, and other foreign compounds in
biological and related specimens. Assuming only basic knowledge of
analytical chemistry, this invaluable guide helps trainee
analytical toxicologists understand the principles and practical
skills involved in detecting, identifying, and measuring a broad
range of compounds in various biological samples. Clear,
easy-to-read chapters provide detailed information on topics
including sample collection and preparation, spectrophotometric and
luminescence techniques, liquid and gas-liquid chromatography, and
mass spectrometry including hyphenated techniques. This new edition
contains thoroughly revised content that reflects contemporary
practices and advances in analytical methods. Expanding the scope
of the 1995 World Health Organization (WHO) basic analytical
toxicology manual, the text includes coverage of separation
science, essential pharmacokinetics, xenobiotic absorption,
distribution and metabolism, clinical toxicological and substance
misuse testing, therapeutic drug monitoring, trace elements and
toxic metals analysis, and importantly the clinical interpretation
of analytical results. Written by a prominent team of experienced
practitioners, this volume: Focuses on analytical, statistical, and
pharmacokinetic principles Describes basic methodology, including
colour tests and immunoassay and enzyme-based assays Outlines
laboratory operations, such as method validation, quality
assessment, staff training, and laboratory accreditation Follows
IUPAC nomenclature for chemical names and recommended International
Non-proprietary Name (rINN) for drugs and pesticides Includes
discussion of 'designer drugs' (novel pharmaceutical substances
NPS) Fundamentals of Analytical Toxicology: Clinical and Forensic,
2nd Edition is an indispensable resource for advanced students and
trainee analytical toxicologists across disciplines, such as
clinical science, analytical chemistry, forensic science,
pathology, applied biology, food safety, and pharmaceutical and
pesticide development.
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