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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Biophysics of the Failing Heart - Physics and Biology of Heart Muscle (Hardcover, 2013 ed.)
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Biophysics of the Failing Heart - Physics and Biology of Heart Muscle (Hardcover, 2013 ed.)
Series: Biological and Medical Physics, Biomedical Engineering
Expected to ship within 12 - 17 working days
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Subjects in the monograph "Biophysics of the Failing Heart" include
state of the art chapters considering major biophysical mechanisms
for why hearts responding to acquired or inherited stressors enter
into maladaptive processes eventually leading to an inability of
the heart to respond efficiently to hemodynamic loads especially
during exercise. The chapters describe biophysical techniques that
have been applied to determine the triggers for the heart failure
process as well as the mechanisms for sustaining the disorders.
These techniques include measurements of active and passive
mechanical properties and hemodynamics at levels of organization
ranging from molecules to hearts beating in situ. Biophysical
concepts and approaches are also applied to determination of
signaling and signal transduction, energetics, ionic currents,
transport processes, electro-chemical and chemo-mechanical
coupling. By its emphasis on biophysical aspects of a prevalent
clinical condition, the monograph is unique in its perspective and
focus. The breadth of information in the chapters all in one place
will be of value to clinicians and researchers at all levels.
Modern research approaches and clinical understanding of heart
failure demands integration of multiple aspects of the disorders.
In most cases, combinations of clinician scientists and researchers
author the chapters. A main benefit of the book is couched in its
didactic approach together with its emphasis on how biophysical
concepts and techniques aid in diagnosis and development of new
therapies.
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