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Marine Sponges: Chemicobiological and Biomedical Applications (Hardcover, 1st ed. 2016)
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Marine Sponges: Chemicobiological and Biomedical Applications (Hardcover, 1st ed. 2016)
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The main focus of this book entitled is to provide an up-to-date
coverage of marine sponges and their significance in the current
era. This book is an attempt to compile an outline of marine sponge
research to date, with specific detail on these bioactive
compounds, and their pharmacological and biomedical applications.
The book encompasses twenty chapters covering various topics
related to Marine Sponges. Initial couple of chapters deal about
the worldwide status of marine sponge research, the recent findings
regarding dynamics of sponges, and several interesting research
areas, that are believed to be deserving of increased attention.
Variety of sponges, their toxicology, metagenomics, pharmaceutical
significance and their possible applications in biomedicine has
been discussed in detail. The second half of this part includes
chapters on chemical ecology of marine sponges followed by the
discussion on importance of bioeroding sponges in aquaculture
systems. The following four chapters of the book deal majorly with
the chemical molecules of marine sponges. In the fifth chapter,
marine sponge-associated actinobacteria and their pysicochemical
properties have been discussed followed by their bioactive
potential. The biological application of marine sponges has been
presented in later chapters with the classification of biologically
active compounds being explored in detail. The second half of the
book presents the vast repertoire of secondary metabolites from
marine sponges, which include terpenoids, heterocycles, acetylenic
compounds, steroids and nucleosides. Further, the bioactive
potential of these compounds has also been discussed. One of the
constituent chapter elaborates the bioactive alkaloids from marine
sponges namely, pyridoacridine, indole, isoquinolene, piperidene,
quinolizidine, steroidal and bromotyrosine alkaloids isolated from
them. In the next couple of chapters, important sponge polymers and
the anticancer effects of marine sponge compounds have been
presented. The most interesting aspect of sponge biology is their
use in biomedical arena. An effort has been made in this book, to
cover the major constituents of sponges and their biomedical
potentials. The major portion of sponge body is composed of
collagen and silica and used in tissue engineering as scaffold
material. This part of the book compiles chapters delineating the
isolation of sponge biomaterials including collagen and their use
in medical diagnostics. Overall, this book would be an important
read for novice and experts in the field of sponge biology.
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