COX-2 Blockade in Cancer Prevention and Therapy (Hardcover, 2003 ed.)

Cylooxygenase 2 (COX-2) Blockade in Cancer Prevention and Therapy documents the converging evidence that COX-2 blocking agents and other nonsteroidal anti-inflammatory drugs (NSAIDs) have chemopreventive and therapuetic effects against virtually all forms of cancer. The book's scope covers historical aspects of the discovery and development of COX-2 blocking agents. It also covers the epidemiologic evidence suggesting that COX-2 inhibitors protect against cancers of the colon, breast, and other anatomic sites; animal and molecular models demonstrating that these compounds block critical steps in carcinogenesis; and pharmacologic findings and clinical applications which are immediately relevant to cancer prevention, therapy, and control. The comprehensive nature of this book makes it an important reference test for applied cancer research and provides a general basis for extended research and development on the antineoplastic properties of COX-2 inhibitors. The text underscores the urgent need for human clinical trials of these compounds in order to expedite their efficacious application in cancer prevention and therapy. Each chapter is written by an expert in the field and documents the latest breaking science and original evidence on COX-2 inhibitors. The book presents a novel approach to cancer prevention and therapy involving compounds which are relatively safe for use by the human population. The cancer prevention and therapy involving compounds have already been approved by the FDA for the treatment of arthritic conditions, pain, and inflammation. These compounds clearly have the potential to reduce the burden of cancer in the human population. The book intends to be a comprehensive reference text for applied cancer research on COX-2 inhibitors and NSAIDs, and provides a general basis for extended research and development of the antineoplastic properties of these compounds and their application in human cancer prevention a

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Cancer Drug Discovery and Development
Release date:	October 2002
First published:	2003
Editors:	Randall E Harris
Dimensions:	254 x 178 x 22mm (L x W x T)
Format:	Hardcover
Pages:	371
Edition:	2003 ed.
ISBN-13:	978-1-58829-010-6
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Promotions
LSN:	1-58829-010-7
Barcode:	9781588290106

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