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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Mouse Models of Cancer - Methods and Protocols (Hardcover, 2015 ed.)
Loot Price: R3,225
Discovery Miles 32 250
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Mouse Models of Cancer - Methods and Protocols (Hardcover, 2015 ed.)
Series: Methods in Molecular Biology, 1267
Expected to ship within 10 - 15 working days
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This volume is essential for geneticists, molecular biologists,
biochemists, and medical doctors interested in the use of mouse
models in cancer research. Recent genome studies, together with
refined genetic engineering techniques, have greatly increased the
value of using mice for research on cancer and other human
disorders. The chapters of this book will support scientists in
choosing the most suitable mouse models for their research
questions. The book provides detailed methodological information
for genetic or chemical induction of different types of cancer,
histomorphometric cancer analysis, and in vivo imaging, as well as
protocols to investigate oncogene addiction, immune surveillance,
and hallmarks of cancer such as angiogenesis or metastasis. Four
review-like articles provide background information on mouse
technologies and histopathologic differences between mouse and
human cancers. The mouse models described in individual chapters
will fuel the understanding of cancer initiation, immune system
roles, tumor angiogenesis, invasion, metastasis, and the relevance
of molecular diversity observed among human cancers. Written in the
highly successful Methods in Molecular Biology series format,
chapters include introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols, and tips on troubleshooting and
avoiding known pitfalls. Cutting-edge and resourceful, Mouse Models
of Cancers: Methods and Protocols, is a valuable laboratory
resource for all researchers, from the graduate level upwards, who
study cancer and new possibilities for its treatment.
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