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The Extracellular Matrix: an Overview (Paperback, 2011 ed.)
Loot Price: R8,604
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The Extracellular Matrix: an Overview (Paperback, 2011 ed.)
Series: Biology of Extracellular Matrix
Expected to ship within 10 - 15 working days
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Knowledge of the extracellular matrix (ECM) is essential to
understand cellular differentiation, tissue development, and tissue
remodeling. This volume of the series "Biology of Extracellular
Matrix" provides a timely overview of the structure, regulation,
and function of the major macromolecules that make up the
extracellular matrix. It covers topics such as collagen types and
assembly of collagen-containing suprastructures, basement membrane,
fibronectin and other cell-adhesive glycoproteins, proteoglycans,
microfibrils, elastin, fibulins and matricellular proteins, such as
thrombospondin. It also explores the concept that ECM components
together with their cell surface receptors can be viewed as
intricate nano-devices that allow cells to physically organize
their 3-D-environment. Further, the role of the ECM in human
disease and pathogenesis is discussed as well as the use of model
organisms in elucidating ECM function.
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