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Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins
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Approaches to the Conformational Analysis of Biopharmaceuticals (Paperback)
Loot Price: R2,367
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Approaches to the Conformational Analysis of Biopharmaceuticals (Paperback)
Series: Protein Science
Expected to ship within 12 - 19 working days
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The activity of many biopharmaceutical polymers is dependent on
conformation, and the next several years will see increased
interest in the conformational analysis of these polymers resulting
from the development of biosimilar or "follow-on" biological
products. While a wide variety of approaches to analysis exists,
finding the most viable ones would be much easier with a
consolidated reference that details the benefits and cost of each
approach, with an emphasis on real results and real products.
Explores the Growing Role of Conformational Analysis in Comparing
Generic Biopharmaceuticals Approaches to the Conformational
Analysis of Biopharmaceuticals gathers the most useful techniques
and methods into a single volume, putting the greatest emphasis on
those approaches that have proven the most fruitful. Rather than
cover specific uses of techniques in detail, this book provides
commercial biotechnologists and researchers with the information
and references they need to make good choices about the technology
they choose to use. With a large number of references that direct
readers to primary source material, it includes studies drawn from
the gamut of current literature, covering physical methods, such as
differential scanning calorimetry, light scanning, and analytical
ultracentrifugation. It also addresses chemical methods, such as
hydrogen-deuterium exchange and trace labeling, along with
infrared, ultraviolet, and Raman spectroscopy. Written by Roger
Lundblad, a true pioneer in protein science, this volume supplies
the necessary information researchers need to access when deciding
on the most cost-effective approach, including: Comparability of
biopharmaceuticals Characterization of follow-on biologics Quality
attributes of protein biopharmaceuticals Confrontational analysis
of biopharmaceutical products With a clear focus on relevant
commercial biotechnology, this book belongs on the shelves of those
serious researchers who are paving the way for the next generation
of biopharmaceutical polymers.
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