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Management of Chemotherapy-Induced Nausea and Vomiting - New Agents and New Uses of Current Agents (Hardcover, 1st ed. 2016)
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Management of Chemotherapy-Induced Nausea and Vomiting - New Agents and New Uses of Current Agents (Hardcover, 1st ed. 2016)
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This book provides a comprehensive review of new agents, a detailed
description of new uses of current agents, and an integration of
the available agents in clinical practice. A description of a
detailed clinical approach provides clinical practitioners with the
most up-to-date recommendations for the prevention and treatment of
chemotherapy-induced nausea and vomiting (CINV) in various clinical
settings. CINV is one of the most feared treatment related
toxicities. Patient surveys for the past thirty years consistently
demonstrate patients' perception of deterioration in quality of
life due to chemotherapy treatments. The introduction of the
antiemetics, serotonin 5-HT3 receptor antagonists and the
neurokinin-1 receptor antagonists, have improved the control of
chemotherapy-induced emesis, but the treatment of
chemotherapy-induced nausea remains a significant clinical problem.
Patients continue to have quality of life issues which prevent
normal functioning during active treatment. New agents such as the
second generation 5-HT3 receptor antagonist palonosetron and the
new neuroknin-1 receptor antagonists rolapitant and netupitant are
being introduced into clinical practice, and it is anticipated that
these new agents will improve the control of CINV. Agents such as
olanzapine (a FDA approved anti-psychotic), gabapentin (a FDA
approved neuroleptic), and ginger (a food additive), which have
been used primarily for other indications, are now being tested as
potential, effective antiemetics. This work represents the first
available comprehensive summary that details all new antiemetic
agents and, particularly, their clinical role in treating patients;
an important reference for practitioners seeking to improve the
quality of life of patients undergoing chemotherapy.
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