Over the past 50 years a wide variety of antibacterial substances
have been discovered and synthesised, and their use in treating
bacterial infection has been spectacularly successful. Today there
are several general classes of antibacterial drugs, each having a
well established set of uses, and together they form the mainstay
of modern antibacterial chemotherapy. In search for new and
improved agents, the pharmaceutical researcher needs to be well
informed on many topics, including existing agents, their modes of
action and pharmacology, and possible synthetic approaches. In this
new book the author has brought together a wide range of
information on the principal classes of antibacterial agents, and
he covers, for each group, their history, mode of action, key
structural features, synthesis and bacterial resistance. The result
is a compact and concise overview of these very important classes
of antibacterial agents.
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