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Dermatokinetics of Therapeutic Agents (Hardcover, New)
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Dermatokinetics of Therapeutic Agents (Hardcover, New)
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Novel drug delivery technologies strive to bypass challenging
biological layers to elicit desired pharmacological activity. The
skin, one of our key defensive barriers, is imperfect, and may
allow certain topically applied substances or toxins to pass. The
dermatokinetics of a drug determines the efficacy of treatment of
skin disorders. Presenting the first comprehensive reference on
this important area of research, Dermatokinetics of Therapeutic
Agents includes a general overview of the theoretical as well as
practical aspects of dermatokinetics and addresses the impact of
nature of a drug delivery system on the dermatokinetics of drugs.
Chapters and illustrations cover the introductory aspects
significance, methods, and models used in dermatokinetic studies of
therapeutic agents. Topics include: * Theoretical Models for
Dermatokinetics of Therapeutic Agents * Drug Delivery Approaches to
Modulate Dermatokinetics of Drugs * Conventional Methods of
Cutaneous Drug Sampling * Cutaneous Microdialysis * Sampling
Substrates by Skin Permeabilization * Spectroscopic Techniques in
Dermatokinetics Studies * Regulatory Perspective of Dermatokinetic
Studies
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