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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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Development and Regeneration of the Nervous System (Paperback, Softcover reprint of the original 1st ed. 1992)
Loot Price: R5,866
Discovery Miles 58 660
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Development and Regeneration of the Nervous System (Paperback, Softcover reprint of the original 1st ed. 1992)
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This book explores aspects of the development and regeneration of
the of the rote nervaus system, beginning with fundamental
considerations of borneobox genes in vertebrate pattern formation.
Two papers em- phasize the roJe of mause Hox genes in patterning:
the Hox-2 complex in the branchial arches and Hox-7 at later stages
of development, par- ticularly in the spinal cord and brain. The
importance of borneobox genes and other transcription factors in
patterning the Drosophila embryo is weil known. With the discovery
of homologaus genes in higher verte- brates including man, we now
possess the molecular tools to begin to investigate the molecular
basis of patterning in higher vertebrate em- bryos. Interestingly,
the last few years have seen the discovery of a number of diverged
borneobox genes and other transcription factors in the head, such
genes being arranged in a segmental pattern within the developing
rhombomeres of the brain and such compartmentalization of
expression being extended to their derivatives, tagether with those
of the neural crest. More recently, both Hox genes and Pax genes
have been described in a segmental arrangement as far torward as
the developing forebrain. The majority of the book deals with
regeneration of the nervaus system. Several aspects are explored,
including ways of promoting central nervous system axons to grow
back into a degenerating environment, for example by the use of
complex polymeric matrices.
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