Farnesyltransferase Inhibitors in Cancer Therapy (Paperback, Softcover reprint of the original 1st ed. 2001)

Cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farensyltransferase inhibitors (FTIs); geranylgeranyltransferase inhibitors (GGTIs) are also discussed as potential anticancer drugs. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other cytotoxic agents, such as gemcitabine, cisplatin, and taxanes. Illuminating and richly detailed, Farnesyltransferase Inhibitors in Cancer Therapy constitutes today's standard reference for the pathbreaking use of FTIs and GGTIs in anticancer therapy and offers basic and clinical investigators a comprehensive treatment of the scientific and medical aspects of farnesyltransferase inhibitors.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Cancer Drug Discovery and Development
Release date:	November 2012
First published:	2001
Editors:	Said M. Sebti • Andrew D. Hamilton
Dimensions:	254 x 178 x 16mm (L x W x T)
Format:	Paperback
Pages:	280
Edition:	Softcover reprint of the original 1st ed. 2001
ISBN-13:	978-1-4684-9606-2
Categories:	Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-4684-9606-9
Barcode:	9781468496062

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