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Books > Science & Mathematics > Biology, life sciences > Biochemistry
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In Silico Models for Drug Discovery (Paperback, Softcover reprint of the original 1st ed. 2013)
Loot Price: R4,074
Discovery Miles 40 740
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In Silico Models for Drug Discovery (Paperback, Softcover reprint of the original 1st ed. 2013)
Series: Methods in Molecular Biology, 993
Expected to ship within 10 - 15 working days
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Infectious diseases caused by viruses, parasites, bacteria, and
fungi are the number one cause of death worldwide. Although new
technologies have improved diagnosis of infectious diseases, the
efficacy of all known current anti-infective agents is threatened
by the spread of drug-resistant forms of the pathogens. Hence,
there remains an urgent need to develop anti-infective agents that
target drug-resistant pathogens. In Silico Models for Drug
Discovery presents a comprehensive look at the role in silico
models play in understanding infectious diseases and in developing
novel therapeutics to treat them. Written by leading experts in the
field, chapters cover topics such as techniques to derive novel
antimicrobial targets, methods of interpreting
polypharmacology-based drug target networks, and molecular dynamics
techniques used to compute binding energies of drugs to their
target proteins, to name a few. Written in the successful Methods
in Molecular Biology (TM) series or in review article format,
chapters include introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible protocols, and notes on troubleshooting and avoiding
known pitfalls. Authoritative and easily accessible, In Silico
Models for Drug Discovery seeks to serve both professionals and
novices involved in the study and treatment of infectious diseases.
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