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Protein Sequence Determination - A Sourcebook of Methods and Techniques (Paperback, 2nd ed. 1975. Softcover reprint of the original 2nd ed. 1975)
Loot Price: R2,841
Discovery Miles 28 410
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Protein Sequence Determination - A Sourcebook of Methods and Techniques (Paperback, 2nd ed. 1975. Softcover reprint of the original 2nd ed. 1975)
Series: Molecular Biology, Biochemistry and Biophysics Molekularbiologie, Biochemie und Biophysik, 8
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Total price: R2,851
Discovery Miles: 28 510
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In the few years since the first edition of this book made its
appearance, under takings in the area of protein sequence
determination have increased at an almost logarithmic pace. The
logic governing such efforts has, predictably, retreated from a
simple sense of curiosity in achieving something that had not
previously been done, to be replaced by an absolute requirement for
sequence information as the best means for understanding heretofore
unattainable aspects of chemical, and structural and functional
mechanistic phenomena. Witness, for example, recent volumes of the
Annual Review of Biochemistry and other review journals, which
treat the genetic control of mitochondrial proteins, mechanisms of
enzyme action, the immunochemistry of collagen, and the role of
lysosomal enzymes in the lipid storage diseases - all on the basis
of known protein sequence information. One must note, too, the
appearance of related works in the area of nucleic acid sequencing.
The technologic advances in chemical sequencing procedures have
proliferated at a remarkable rate. It is in the area of
instrumentation, however, that the greatest advances have taken
place. As a consequence of this, each chapter (with one single
exception) in this book has been extensively revised and updated.
Entire chapters have been replaced in several cases, without
minimizing the value of their original content. In addition, a
second volume will appear soon, dealing with subjects not covered
in the present book."
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